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Host and tumor derived MMP13 regulate extravasation and establishment of colorectal metastases in the liver

BACKGROUND: Non alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the United States and worldwide. Our studies have previously shown an increase in metastatic burden in steatotic vs. normal livers using a mouse model of diet induced steatosis. In the present study we...

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Detalles Bibliográficos
Autores principales: Mendonsa, Alisha M, VanSaun, Michael N, Ustione, Alessandro, Piston, David W, Fingleton, Barbara M, Gorden, David Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351934/
https://www.ncbi.nlm.nih.gov/pubmed/25880591
http://dx.doi.org/10.1186/s12943-014-0282-0