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Host and tumor derived MMP13 regulate extravasation and establishment of colorectal metastases in the liver
BACKGROUND: Non alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the United States and worldwide. Our studies have previously shown an increase in metastatic burden in steatotic vs. normal livers using a mouse model of diet induced steatosis. In the present study we...
Autores principales: | Mendonsa, Alisha M, VanSaun, Michael N, Ustione, Alessandro, Piston, David W, Fingleton, Barbara M, Gorden, David Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351934/ https://www.ncbi.nlm.nih.gov/pubmed/25880591 http://dx.doi.org/10.1186/s12943-014-0282-0 |
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