Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity

Trypanosoma brucei variant surface glycoproteins (VSG) are glycosylated by both paucimannose and oligomannose structures which are involved in the formation of a protective barrier against the immune system. Here, we report that the stinging nettle lectin (UDA), with predominant N-acetylglucosamine-...

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Detalles Bibliográficos
Autores principales: Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., Van Damme, Els J. M., Balzarini, Jan, González-Pacanowska, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351956/
https://www.ncbi.nlm.nih.gov/pubmed/25746926
http://dx.doi.org/10.1371/journal.pntd.0003612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351956/
https://www.ncbi.nlm.nih.gov/pubmed/25746926
http://dx.doi.org/10.1371/journal.pntd.0003612

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