Cargando…

Mouse SIRT3 Attenuates Hypertrophy-Related Lipid Accumulation in the Heart through the Deacetylation of LCAD

Cardiac hypertrophy is an adaptive response to pressure, volume stress, and loss of contractile mass from prior infarction. Metabolic changes in cardiac hypertrophy include suppression of fatty acid oxidation and enhancement of glucose utilization, which could result in lipid accumulation in the hea...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Tongshuai, Liu, Junni, Li, Na, Wang, Shujian, Liu, Hui, Li, Jingyuan, Zhang, Yun, Bu, Peili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351969/
https://www.ncbi.nlm.nih.gov/pubmed/25748450
http://dx.doi.org/10.1371/journal.pone.0118909