SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth In Vivo by Inducing G2/M Cell Cycle Arrest

Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target for the development of anticancer therapy. Despite recent advancement in the development of potent and selective PKD small molecule inhibitors, the availability of in vivo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tandon, Manuj, Salamoun, Joseph M., Carder, Evan J., Farber, Elisa, Xu, Shuping, Deng, Fan, Tang, Hua, Wipf, Peter, Wang, Q. Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352033/
https://www.ncbi.nlm.nih.gov/pubmed/25747583
http://dx.doi.org/10.1371/journal.pone.0119346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352033/
https://www.ncbi.nlm.nih.gov/pubmed/25747583
http://dx.doi.org/10.1371/journal.pone.0119346

Ejemplares similares