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SD-208, a Novel Protein Kinase D Inhibitor, Blocks Prostate Cancer Cell Proliferation and Tumor Growth In Vivo by Inducing G2/M Cell Cycle Arrest
Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target for the development of anticancer therapy. Despite recent advancement in the development of potent and selective PKD small molecule inhibitors, the availability of in vivo...
Autores principales: | Tandon, Manuj, Salamoun, Joseph M., Carder, Evan J., Farber, Elisa, Xu, Shuping, Deng, Fan, Tang, Hua, Wipf, Peter, Wang, Q. Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352033/ https://www.ncbi.nlm.nih.gov/pubmed/25747583 http://dx.doi.org/10.1371/journal.pone.0119346 |
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