A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex

The Structural Maintenance of Chromosome (SMC) complex, termed cohesin, is essential for sister chromatid cohesion. Cohesin is also important for chromosome condensation, DNA repair, and gene expression. Cohesin is comprised of Scc3, Mcd1, Smc1, and Smc3. Scc3 also binds Pds5 and Wpl1, cohesin-assoc...

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Detalles Bibliográficos
Autores principales: Orgil, Ola, Matityahu, Avi, Eng, Thomas, Guacci, Vincent, Koshland, Douglas, Onn, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352044/
https://www.ncbi.nlm.nih.gov/pubmed/25748820
http://dx.doi.org/10.1371/journal.pgen.1005036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352044/
https://www.ncbi.nlm.nih.gov/pubmed/25748820
http://dx.doi.org/10.1371/journal.pgen.1005036

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