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HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy
Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington’s disease (HD). While HD has been described primarily as a...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352047/ https://www.ncbi.nlm.nih.gov/pubmed/25748626 http://dx.doi.org/10.1371/journal.pgen.1005021 |