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HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington’s disease (HD). While HD has been described primarily as a...

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Detalles Bibliográficos
Autores principales: Mielcarek, Michal, Toczek, Marta, Smeets, Cleo J. L. M., Franklin, Sophie A., Bondulich, Marie K., Jolinon, Nelly, Muller, Thomas, Ahmed, Mhoriam, Dick, James R. T., Piotrowska, Izabela, Greensmith, Linda, Smolenski, Ryszard T., Bates, Gillian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352047/
https://www.ncbi.nlm.nih.gov/pubmed/25748626
http://dx.doi.org/10.1371/journal.pgen.1005021