Improved Development of Somatic Cell Cloned Mouse Embryos by Vitamin C and Latrunculin A
Impaired development of embryos produced by somatic cell nuclear transfer (SCNT) is mostly associated with faulty reprogramming of the somatic nucleus to a totipotent state and can be improved by treatment with epigenetic modifiers. Here we report that addition of 100 μM vitamin C (VitC) to embryo c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352067/ https://www.ncbi.nlm.nih.gov/pubmed/25749170 http://dx.doi.org/10.1371/journal.pone.0120033 |