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Genome editing in plants via designed zinc finger nucleases

The ability to create DNA double-strand breaks (DSBs) at specified genomic locations, which then stimulate the cell’s naturally occurring DNA repair processes, has introduced intriguing possibilities for genetic modification. Zinc finger nucleases (ZFNs) are designed restriction enzymes consisting o...

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Detalles Bibliográficos
Autor principal: Petolino, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352198/
https://www.ncbi.nlm.nih.gov/pubmed/25774080
http://dx.doi.org/10.1007/s11627-015-9663-3