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Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium

BACKGROUND: Surfactant protein D (SP-D), a pattern recognition molecule, has been shown to play roles in host defense such as opsonisation, aggregation of pathogens, and modulation of the inflammatory response. In light of infection-induced exacerbations and damage to the airway epithelium from infl...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Singhera, Gurpreet K, Dorscheid, Delbert R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352233/
https://www.ncbi.nlm.nih.gov/pubmed/25848896
http://dx.doi.org/10.1186/s12931-015-0177-7