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NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma

NHERF1/EBP50, an adaptor protein required for epithelial morphogenesis, has been implicated in the progression of various human malignancies. NHERF1-deficient mice have intestinal brush border structural defects and we report here that they also have disorganized ependymal cilia with development of...

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Detalles Bibliográficos
Autores principales: Georgescu, Maria-Magdalena, Yell, Paul, Mobley, Bret C, Shang, Ping, Georgescu, Theodora, Wang, Shih-Hsiu J, Canoll, Peter, Hatanpaa, Kimmo J, White III, Charles L, Raisanen, Jack M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352254/
https://www.ncbi.nlm.nih.gov/pubmed/25775275
http://dx.doi.org/10.1186/s40478-015-0197-z