A small molecule activator of AKT does not reduce ischemic injury of the rat heart

BACKGROUND: Activation of protein kinase AKT is required for cardioprotection by ischemic preconditioning, and transgenic overexpression of AKT protects the heart against ischemia. However, it is unknown whether acute pharmacological activation of AKT alone, using a therapeutically relevant strategy...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreira, Jose BN, Wohlwend, Martin, Alves, Marcia NM, Wisløff, Ulrik, Bye, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352273/
https://www.ncbi.nlm.nih.gov/pubmed/25889299
http://dx.doi.org/10.1186/s12967-015-0444-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352273/
https://www.ncbi.nlm.nih.gov/pubmed/25889299
http://dx.doi.org/10.1186/s12967-015-0444-x

Ejemplares similares