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Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

BACKGROUND: The treatment of traumatic brain injury (TBI) represents an unmet medical need, as no effective pharmacological treatment currently exists. The development of such a treatment requires a fundamental understanding of the pathophysiological mechanisms that underpin the sequelae resulting f...

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Detalles Bibliográficos
Autores principales: Baratz, Renana, Tweedie, David, Wang, Jia-Yi, Rubovitch, Vardit, Luo, Weiming, Hoffer, Barry J, Greig, Nigel H, Pick, Chaim G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352276/
https://www.ncbi.nlm.nih.gov/pubmed/25879458
http://dx.doi.org/10.1186/s12974-015-0237-4