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Human CD38(hi)CD138(+) Plasma Cells Can Be Generated In Vitro from CD40-Activated Switched-Memory B Lymphocytes
B lymphocyte differentiation into long-lived plasma cells is the keystone event for the production of long-term protective antibodies. CD40-CD154 and CD27-CD70 interactions are involved in human B lymphocyte differentiation into CD38(hi)CD138(+) cells in vivo as well as in vitro. In this study, we h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352507/ https://www.ncbi.nlm.nih.gov/pubmed/25759831 http://dx.doi.org/10.1155/2014/635108 |