Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging

BACKGROUND: Leishmania use exosomes to communicate with their mammalian hosts and these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence factors to macrophages. In other eukaryotes, exosomes were found to carry RNA cargo, such as mRNAs and small non-coding RNAs,...

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Detalles Bibliográficos
Autores principales: Lambertz, Ulrike, Oviedo Ovando, Mariana E, Vasconcelos, Elton JR, Unrau, Peter J, Myler, Peter J, Reiner, Neil E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352550/
https://www.ncbi.nlm.nih.gov/pubmed/25764986
http://dx.doi.org/10.1186/s12864-015-1260-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352550/
https://www.ncbi.nlm.nih.gov/pubmed/25764986
http://dx.doi.org/10.1186/s12864-015-1260-7

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