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Identification of a novel type of small molecule inhibitor against HIV-1
Here we report a new chemical inhibitor against HIV-1 with a novel structure and mode of action. The inhibitor, designated as A1836, inhibited HIV-1 replication and virus production with a 50% inhibitory concentration (IC(50)) of 2.0 μM in an MT-4 cell-based and cytopathic protection antiviral assay...
Autores principales: | Kim, Byung Soo, Park, Jung Ae, Kim, Min-Jung, Kim, Seon Hee, Yu, Kyung Lee, You, Ji Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352614/ https://www.ncbi.nlm.nih.gov/pubmed/25413304 http://dx.doi.org/10.5483/BMBRep.2015.48.2.239 |
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