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Structure and apoptotic function of p73

p73 is a structural and functional homologue of the p53 tumor suppressor protein. Like p53, p73 induces apoptosis and cell cycle arrest and transactivates p53-responsive genes, conferring its tumor suppressive activity. In addition, p73 has unique roles in neuronal development and differentiation. T...

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Detalles Bibliográficos
Autores principales: Yoon, Mi-Kyung, Ha, Ji-Hyang, Lee, Min-Sung, Chi, Seung-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352617/
https://www.ncbi.nlm.nih.gov/pubmed/25441426
http://dx.doi.org/10.5483/BMBRep.2015.48.2.255