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Error-Free DNA Damage Tolerance and Sister Chromatid Proximity during DNA Replication Rely on the Polα/Primase/Ctf4 Complex

Chromosomal replication is entwined with DNA damage tolerance (DDT) and chromatin structure establishment via elusive mechanisms. Here we examined how specific replication conditions affecting replisome architecture and repriming impact on DDT. We show that Saccharomyces cerevisiae Polα/Primase/Ctf4...

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Detalles Bibliográficos
Autores principales: Fumasoni, Marco, Zwicky, Katharina, Vanoli, Fabio, Lopes, Massimo, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352764/
https://www.ncbi.nlm.nih.gov/pubmed/25661486
http://dx.doi.org/10.1016/j.molcel.2014.12.038