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Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

Drug discovery and development are hampered by high failure rates attributed to the reliance on non-human animal models employed during safety and efficacy testing. A fundamental problem in this inefficient process is that non-human animal models cannot adequately represent human biology. Thus, ther...

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Detalles Bibliográficos
Autores principales: Mathur, Anurag, Loskill, Peter, Shao, Kaifeng, Huebsch, Nathaniel, Hong, SoonGweon, Marcus, Sivan G., Marks, Natalie, Mandegar, Mohammad, Conklin, Bruce R., Lee, Luke P., Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352848/
https://www.ncbi.nlm.nih.gov/pubmed/25748532
http://dx.doi.org/10.1038/srep08883