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A Dual-Reporter System for Real-Time Monitoring and High-throughput CRISPR/Cas9 Library Screening of the Hepatitis C Virus

The hepatitis C virus (HCV) is one of the leading causes of chronic hepatitis, liver cirrhosis and hepatocellular carcinomas and infects approximately 170 million people worldwide. Although several reporter systems have been developed, many shortcomings limit their use in the assessment of HCV infec...

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Detalles Bibliográficos
Autores principales: Ren, Qingpeng, Li, Chan, Yuan, Pengfei, Cai, Changzu, Zhang, Linqi, Luo, Guangxiang George, Wei, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352851/
https://www.ncbi.nlm.nih.gov/pubmed/25746010
http://dx.doi.org/10.1038/srep08865