Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling

Increasing bacterial resistance to available antibiotics makes the discovery of novel efficacious antibacterial agents a priority. A previous report showed that listeriolysin O (LLO) is a critical virulence factor and suggested that it is a target for developing anti-virulence drugs against Listeria...

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Detalles Bibliográficos
Autores principales: Wang, Jianfeng, Zhou, Xuan, Liu, Shui, Li, Gen, Zhang, Bing, Deng, Xuming, Niu, Xiaodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352855/
https://www.ncbi.nlm.nih.gov/pubmed/25749652
http://dx.doi.org/10.1038/srep08864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352855/
https://www.ncbi.nlm.nih.gov/pubmed/25749652
http://dx.doi.org/10.1038/srep08864

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