Metabolomic identification of biochemical changes induced by fluoxetine and imipramine in a chronic mild stress mouse model of depression

Metabolomics was applied to a C57BL/6N mouse model of chronic unpredictable mild stress (CMS). Such mice were treated with two antidepressants from different categories: fluoxetine and imipramine. Metabolic profiling of the hippocampus was performed using gas chromatography-mass spectrometry analysi...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Jung, Yang-Hee, Jang, Choon-Gon, Chun, Kwang-Hoon, Kwon, Sung Won, Lee, Jeongmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352870/
https://www.ncbi.nlm.nih.gov/pubmed/25749400
http://dx.doi.org/10.1038/srep08890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352870/
https://www.ncbi.nlm.nih.gov/pubmed/25749400
http://dx.doi.org/10.1038/srep08890

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