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Metabolomic identification of biochemical changes induced by fluoxetine and imipramine in a chronic mild stress mouse model of depression
Metabolomics was applied to a C57BL/6N mouse model of chronic unpredictable mild stress (CMS). Such mice were treated with two antidepressants from different categories: fluoxetine and imipramine. Metabolic profiling of the hippocampus was performed using gas chromatography-mass spectrometry analysi...
Autores principales: | Zhao, Jing, Jung, Yang-Hee, Jang, Choon-Gon, Chun, Kwang-Hoon, Kwon, Sung Won, Lee, Jeongmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352870/ https://www.ncbi.nlm.nih.gov/pubmed/25749400 http://dx.doi.org/10.1038/srep08890 |
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