Cargando…

DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences

Integration of DNA viruses into the human genome plays an important role in various types of tumors, including hepatitis B virus (HBV)–related hepatocellular carcinoma. However, the molecular details and clinical impact of HBV integration on either human or HBV epigenomes are unknown. Here, we show...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Yoshiyuki, Yamamoto, Hiroyuki, Oikawa, Ritsuko, Toyota, Minoru, Yamamoto, Masakazu, Kokudo, Norihiro, Tanaka, Shinji, Arii, Shigeki, Yotsuyanagi, Hiroshi, Koike, Kazuhiko, Itoh, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352876/
https://www.ncbi.nlm.nih.gov/pubmed/25653310
http://dx.doi.org/10.1101/gr.175240.114