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DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences

Integration of DNA viruses into the human genome plays an important role in various types of tumors, including hepatitis B virus (HBV)–related hepatocellular carcinoma. However, the molecular details and clinical impact of HBV integration on either human or HBV epigenomes are unknown. Here, we show...

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Detalles Bibliográficos
Autores principales:	Watanabe, Yoshiyuki, Yamamoto, Hiroyuki, Oikawa, Ritsuko, Toyota, Minoru, Yamamoto, Masakazu, Kokudo, Norihiro, Tanaka, Shinji, Arii, Shigeki, Yotsuyanagi, Hiroshi, Koike, Kazuhiko, Itoh, Fumio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352876/ https://www.ncbi.nlm.nih.gov/pubmed/25653310 http://dx.doi.org/10.1101/gr.175240.114

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