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A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

Genomic imprinting is an epigenetic mechanism that restrains the expression of ∼100 eutherian genes in a parent-of-origin-specific manner. The reason for this selective targeting of genes with seemingly disparate molecular functions is unclear. In the present work, we show that imprinted genes are c...

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Detalles Bibliográficos
Autores principales: Al Adhami, Hala, Evano, Brendan, Le Digarcher, Anne, Gueydan, Charlotte, Dubois, Emeric, Parrinello, Hugues, Dantec, Christelle, Bouschet, Tristan, Varrault, Annie, Journot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352888/
https://www.ncbi.nlm.nih.gov/pubmed/25614607
http://dx.doi.org/10.1101/gr.175919.114