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Src inhibitor reduces permeability without disturbing vascularization and prevents bone destruction in steroid-associated osteonecrotic lesions in rabbits

To examine the therapeutic effect of Src inhibitor on the VEGF mediating vascular hyperpermeability and bone destruction within steroid-associated osteonecrotic lesions in rabbits. Rabbits with high risk for progress to destructive repair in steroid-associated osteonecrosis were selected according t...

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Detalles Bibliográficos
Autores principales: He, Yi-Xin, Liu, Jin, Guo, Baosheng, Wang, Yi-Xiang, Pan, Xiaohua, Li, Defang, Tang, Tao, Chen, Yang, Peng, Songlin, Bian, Zhaoxiang, Liang, Zicai, Zhang, Bao-Ting, Lu, Aiping, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352921/
https://www.ncbi.nlm.nih.gov/pubmed/25748225
http://dx.doi.org/10.1038/srep08856