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CD47 Deficiency Protects Mice From Diet-induced Obesity and Improves Whole Body Glucose Tolerance and Insulin Sensitivity

CD47 is a transmembrane protein with several functions including self-recognition, immune cell communication, and cell signaling. Although it has been extensively studied in cancer and ischemia, CD47 function in obesity has never been explored. In this study, we utilized CD47 deficient mice in a hig...

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Detalles Bibliográficos
Autores principales: Maimaitiyiming, Hasiyeti, Norman, Heather, Zhou, Qi, Wang, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352923/
https://www.ncbi.nlm.nih.gov/pubmed/25747123
http://dx.doi.org/10.1038/srep08846