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Porphyromonas gingivalis Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk

Signaling via pattern recognition receptors (PRRs) expressed on professional antigen presenting cells, such as dendritic cells (DCs), is crucial to the fate of engulfed microbes. Among the many PRRs expressed by DCs are Toll-like receptors (TLRs) and C-type lectins such as DC-SIGN. DC-SIGN is target...

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Detalles Bibliográficos
Autores principales: El-Awady, Ahmed R., Miles, Brodie, Scisci, Elizabeth, Kurago, Zoya B., Palani, Chithra D., Arce, Roger M., Waller, Jennifer L., Genco, Caroline A., Slocum, Connie, Manning, Matthew, Schoenlein, Patricia V., Cutler, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352937/
https://www.ncbi.nlm.nih.gov/pubmed/25679217
http://dx.doi.org/10.1371/journal.ppat.1004647