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Wnt ligands from the embryonic surface ectoderm regulate ‘bimetallic strip’ optic cup morphogenesis in mouse

The Wnt/β-catenin response pathway is central to many developmental processes. Here, we assessed the role of Wnt signaling in early eye development using the mouse as a model system. We showed that the surface ectoderm region that includes the lens placode expressed 12 out of 19 possible Wnt ligands...

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Detalles Bibliográficos
Autores principales: Carpenter, April C., Smith, April N., Wagner, Heidi, Cohen-Tayar, Yamit, Rao, Sujata, Wallace, Valerie, Ashery-Padan, Ruth, Lang, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352985/
https://www.ncbi.nlm.nih.gov/pubmed/25715397
http://dx.doi.org/10.1242/dev.120022