Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

Modification of proteins with ubiquitin (Ub) occurs through a variety of topologically distinct Ub linkages, including Ube2W-mediated monoubiquitylation of N-terminal alpha amines to generate peptide-linked linear mono-Ub fusions. Protein ubiquitylation can be reversed by the action of deubiquitylat...

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Detalles Bibliográficos
Autores principales: Bett, John S., Ritorto, Maria Stella, Ewan, Richard, Jaffray, Ellis G., Virdee, Satpal, Chin, Jason W., Knebel, Axel, Kurz, Thimo, Trost, Matthias, Tatham, Michael H., Hay, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353193/
https://www.ncbi.nlm.nih.gov/pubmed/25489924
http://dx.doi.org/10.1042/BJ20141349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353193/
https://www.ncbi.nlm.nih.gov/pubmed/25489924
http://dx.doi.org/10.1042/BJ20141349

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