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Cell-to-cell transfer of Leishmania amazonensis amastigotes is mediated by immunomodulatory LAMP-rich parasitophorous extrusions

The last step of Leishmania intracellular life cycle is the egress of amastigotes from the host cell and their uptake by adjacent cells. Using multidimensional live imaging of long-term-infected macrophage cultures we observed that Leishmania amazonensis amastigotes were transferred from cell to cel...

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Detalles Bibliográficos
Autores principales: Real, Fernando, Florentino, Pilar Tavares Veras, Reis, Luiza Campos, Ramos-Sanchez, Eduardo M, Veras, Patricia Sampaio Tavares, Goto, Hiro, Mortara, Renato Arruda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353215/
https://www.ncbi.nlm.nih.gov/pubmed/24824158
http://dx.doi.org/10.1111/cmi.12311