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DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase

Death domain-associated protein 6 (DAXX) is a histone chaperone, putative regulator of apoptosis and transcription, and candidate modulator of p53-mediated gene expression following DNA damage. DAXX becomes phosphorylated upon DNA damage, however regulation of this modification, and its relationship...

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Detalles Bibliográficos
Autores principales: Brazina, Jan, Svadlenka, Jan, Macurek, Libor, Andera, Ladislav, Hodny, Zdenek, Bartek, Jiri, Hanzlikova, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353233/
https://www.ncbi.nlm.nih.gov/pubmed/25659035
http://dx.doi.org/10.4161/15384101.2014.988019