Cargando…
DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase
Death domain-associated protein 6 (DAXX) is a histone chaperone, putative regulator of apoptosis and transcription, and candidate modulator of p53-mediated gene expression following DNA damage. DAXX becomes phosphorylated upon DNA damage, however regulation of this modification, and its relationship...
Autores principales: | Brazina, Jan, Svadlenka, Jan, Macurek, Libor, Andera, Ladislav, Hodny, Zdenek, Bartek, Jiri, Hanzlikova, Hana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353233/ https://www.ncbi.nlm.nih.gov/pubmed/25659035 http://dx.doi.org/10.4161/15384101.2014.988019 |
Ejemplares similares
-
Multifunctional adaptor protein Daxx interacts with chromatin-remodelling ATPase Brg1
por: Svadlenka, Jan, et al.
Publicado: (2015) -
WIP1 phosphatase as pharmacological target in cancer therapy
por: Pecháčková, Soňa, et al.
Publicado: (2017) -
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1
checkpoint
por: Kleiblova, Petra, et al.
Publicado: (2013) -
Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase
por: Shreeram, Sathyavageeswaran, et al.
Publicado: (2006) -
Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3
por: Pechackova, Sona, et al.
Publicado: (2016)