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Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease
Alpha-synuclein is a presynaptic protein expressed throughout the central nervous system, and it is the main component of Lewy bodies, one of the histopathological features of Parkinson's disease (PD) which is a progressive and irreversible neurodegenerative disorder. The conformational flexibi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353246/ https://www.ncbi.nlm.nih.gov/pubmed/25805964 http://dx.doi.org/10.3389/fnins.2015.00059 |