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Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

Alpha-synuclein is a presynaptic protein expressed throughout the central nervous system, and it is the main component of Lewy bodies, one of the histopathological features of Parkinson's disease (PD) which is a progressive and irreversible neurodegenerative disorder. The conformational flexibi...

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Detalles Bibliográficos
Autores principales:	Gallegos, Scarlet, Pacheco, Carla, Peters, Christian, Opazo, Carlos M., Aguayo, Luis G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353246/ https://www.ncbi.nlm.nih.gov/pubmed/25805964 http://dx.doi.org/10.3389/fnins.2015.00059

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