Practical Synthesis of Cytidine-5-Carboxamide-Modified Nucleotide Reagents

Chemically-modified derivatives of cytidine, bearing a 5-(N-substituted-carboxamide) functional group, are new reagents for use in aptamer discovery via the SELEX process (Systematic Evolution of Ligands by EXponential enrichment). Herein, we disclose a practical synthesis of 5-(N-benzylcarboxamide)...

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Detalles Bibliográficos
Autores principales: Rohloff, John C., Fowler, Catherine, Ream, Brian, Carter, Jeffrey D., Wardle, Greg, Fitzwater, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353258/
https://www.ncbi.nlm.nih.gov/pubmed/25710355
http://dx.doi.org/10.1080/15257770.2014.978011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353258/
https://www.ncbi.nlm.nih.gov/pubmed/25710355
http://dx.doi.org/10.1080/15257770.2014.978011

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