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Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo

Enveloped viruses utilize membrane glycoproteins on their surface to mediate entry into host cells. Three-dimensional structural analysis of these glycoprotein ‘spikes’ is often technically challenging but important for understanding viral pathogenesis and in drug design. Here, a protocol is present...

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Detalles Bibliográficos
Autores principales: Huiskonen, Juha T., Parsy, Marie-Laure, Li, Sai, Bitto, David, Renner, Max, Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353292/
https://www.ncbi.nlm.nih.gov/pubmed/25350719
http://dx.doi.org/10.3791/51714