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Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo
Enveloped viruses utilize membrane glycoproteins on their surface to mediate entry into host cells. Three-dimensional structural analysis of these glycoprotein ‘spikes’ is often technically challenging but important for understanding viral pathogenesis and in drug design. Here, a protocol is present...
Autores principales: | Huiskonen, Juha T., Parsy, Marie-Laure, Li, Sai, Bitto, David, Renner, Max, Bowden, Thomas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353292/ https://www.ncbi.nlm.nih.gov/pubmed/25350719 http://dx.doi.org/10.3791/51714 |
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