Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci

Developing chimeric lysins with a wide lytic spectrum would be important for treating some infections caused by multiple pathogenic bacteria. In the present work, a novel chimeric lysin (Ply187N-V12C) was constructed by fusing the catalytic domain (Ply187N) of the bacteriophage lysin Ply187 with the...

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Detalles Bibliográficos
Autores principales: Dong, Qiuhua, Wang, Jing, Yang, Hang, Wei, Cuihua, Yu, Junping, Zhang, Yun, Huang, Yanling, Zhang, Xian-En, Wei, Hongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353335/
https://www.ncbi.nlm.nih.gov/pubmed/25219798
http://dx.doi.org/10.1111/1751-7915.12166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353335/
https://www.ncbi.nlm.nih.gov/pubmed/25219798
http://dx.doi.org/10.1111/1751-7915.12166

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