Production of 2-ketoisocaproate with Corynebacterium glutamicum strains devoid of plasmids and heterologous genes

2-Ketoisocaproate (KIC), the last intermediate in l-leucine biosynthesis, has various medical and industrial applications. After deletion of the ilvE gene for transaminase B in l-leucine production strains of Corynebacterium glutamicum, KIC became the major product, however, the strains were auxotro...

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Detalles Bibliográficos
Autores principales: Vogt, Michael, Haas, Sabine, Polen, Tino, van Ooyen, Jan, Bott, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353348/
https://www.ncbi.nlm.nih.gov/pubmed/25488800
http://dx.doi.org/10.1111/1751-7915.12237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353348/
https://www.ncbi.nlm.nih.gov/pubmed/25488800
http://dx.doi.org/10.1111/1751-7915.12237

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