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Production of 2-ketoisocaproate with Corynebacterium glutamicum strains devoid of plasmids and heterologous genes
2-Ketoisocaproate (KIC), the last intermediate in l-leucine biosynthesis, has various medical and industrial applications. After deletion of the ilvE gene for transaminase B in l-leucine production strains of Corynebacterium glutamicum, KIC became the major product, however, the strains were auxotro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353348/ https://www.ncbi.nlm.nih.gov/pubmed/25488800 http://dx.doi.org/10.1111/1751-7915.12237 |