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Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK)

BACKGROUND: Homeodomain interacting protein kinases (HIPKs) function as modulators of cellular stress responses and regulate cell differentiation, proliferation and apoptosis. The HIPK family includes HIPK1, HIPK2 and HIPK3, which share a similar domain structure, and the more distantly related HIPK...

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Detalles Bibliográficos
Autores principales: van der Laden, Jan, Soppa, Ulf, Becker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353451/
https://www.ncbi.nlm.nih.gov/pubmed/25630557
http://dx.doi.org/10.1186/s12964-014-0082-6