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Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling

BACKGROUND: We previously identified dermicidin (DCD), which encodes a growth and survival factor, as a gene amplified and overexpressed in a subset of breast tumors. Patients with DCD-positive breast cancer have worse prognostic features. We therefore searched for specific molecular signatures in D...

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Detalles Bibliográficos
Autores principales: Bancovik, Jasna, Moreira, Dayson F, Carrasco, Daniel, Yao, Jun, Porter, Dale, Moura, Ricardo, Camargo, Anamaria, Fontes-Oliveira, Cibely C, Malpartida, Miguel G, Carambula, Silvia, Vannier, Edouard, Strauss, Bryan E, Wakamatsu, Alda, Alves, Venancio AF, Logullo, Angela F, Soares, Fernando A, Polyak, Kornelia, Belizário, José E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353460/
https://www.ncbi.nlm.nih.gov/pubmed/25879571
http://dx.doi.org/10.1186/s12885-015-1022-6