Cargando…

Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling

BACKGROUND: We previously identified dermicidin (DCD), which encodes a growth and survival factor, as a gene amplified and overexpressed in a subset of breast tumors. Patients with DCD-positive breast cancer have worse prognostic features. We therefore searched for specific molecular signatures in D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bancovik, Jasna, Moreira, Dayson F, Carrasco, Daniel, Yao, Jun, Porter, Dale, Moura, Ricardo, Camargo, Anamaria, Fontes-Oliveira, Cibely C, Malpartida, Miguel G, Carambula, Silvia, Vannier, Edouard, Strauss, Bryan E, Wakamatsu, Alda, Alves, Venancio AF, Logullo, Angela F, Soares, Fernando A, Polyak, Kornelia, Belizário, José E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353460/ https://www.ncbi.nlm.nih.gov/pubmed/25879571 http://dx.doi.org/10.1186/s12885-015-1022-6

Ejemplares similares

Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6
por: Belizário, José E., et al.
Publicado: (2016)

The role of Dermcidin isoform-2 in the occurrence and severity of Diabetes
por: Bhattacharya, Suman, et al.
Publicado: (2017)

Preclinical Development of Seriniquinones as Selective Dermcidin Modulators for the Treatment of Melanoma
por: Hirata, Amanda S., et al.
Publicado: (2022)

The relation of dermcidin with insulin resistance and inflammation in women with polycystic ovary syndrome
por: Akan, Ozden Yildirim, et al.
Publicado: (2022)

Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L
por: Nguyen, Van Sang, et al.
Publicado: (2017)

A Positive Dermcidin Expression Is an Unfavorable Prognostic Marker for Extramammary Paget’s Disease
por: Ohmori, Shun, et al.
Publicado: (2021)

Dermcidin Enhances the Migration, Invasion, and Metastasis of Hepatocellular Carcinoma Cells In Vitro and In Vivo
por: Qiu, Fanghua, et al.
Publicado: (2022)

Cell Death-Associated Molecular-Pattern Molecules: Inflammatory Signaling and Control
por: Sangiuliano, Beatriz, et al.
Publicado: (2014)

Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide
por: Mikhaylova, Marina, et al.
Publicado: (2014)

Dermcidin expression in hepatic cells improves survival without N-glycosylation, but requires asparagine residues
por: Lowrie, A G, et al.
Publicado: (2006)

Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein
por: Ghosh, Rajeshwary, et al.
Publicado: (2014)

The Human Antimicrobial Peptides Dermcidin and LL-37 Show Novel Distinct Pathways in Membrane Interactions
por: Zeth, Kornelius, et al.
Publicado: (2017)

Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines
por: Stewart, G D, et al.
Publicado: (2008)

Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I–II early‐stage melanoma
por: Ortega‐Martínez, Idoia, et al.
Publicado: (2016)

Human Dermcidin Protects Mice Against Hepatic Ischemia-Reperfusion–Induced Local and Remote Inflammatory Injury
por: Qiang, Xiaoling, et al.
Publicado: (2022)

Lung microbiome and origins of the respiratory diseases
por: Belizário, José, et al.
Publicado: (2023)

Dermcidin isoform-2 induced nullification of the effect of acetyl salicylic acid in platelet aggregation in acute myocardial infarction
por: Bank, Sarbashri, et al.
Publicado: (2014)

Cell surface GRP78 and Dermcidin cooperate to regulate breast cancer cell migration through Wnt signaling
por: Lager, Tyson W., et al.
Publicado: (2021)

A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
por: Tricarico, Paola Maura, et al.
Publicado: (2022)

Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy
por: Belizário, José E., et al.
Publicado: (2016)

Gut Microbiome Dysbiosis and Immunometabolism: New Frontiers for Treatment of Metabolic Diseases
por: Belizário, José E., et al.
Publicado: (2018)

Breath Biopsy and Discovery of Exclusive Volatile Organic Compounds for Diagnosis of Infectious Diseases
por: Belizário, José E., et al.
Publicado: (2021)

The Role of Dermcidin Isoform 2: A Two-Faceted Atherosclerotic Risk Factor for Coronary Artery Disease and the Effect of Acetyl Salicylic Acid on It
por: Ghosh, Rajeshwary, et al.
Publicado: (2012)

Therapy-Resistant, Spontaneously Remitting Generalized Neutrophilic Eccrine Hidradenitis in a Healthy Patient Decreases the Expression of Dermcidin in Affected Eccrine Glands
por: Kambayashi, Yumi, et al.
Publicado: (2011)

Antimicrobial and anti-biofilm potencies of dermcidin-derived peptide DCD-1L against Acinetobacter baumannii: an in vivo wound healing model
por: Farshadzadeh, Zahra, et al.
Publicado: (2022)

Combined use of immunohistochemical markers of basal and luminal subtypes in urothelial carcinoma of the bladder: Association with clinicopathological features and outcomes
por: Ravanini, Juliana Naves, et al.
Publicado: (2021)

El candombe ; danza ritual pantomímica del folklore Afro-Rioplatense
por: Carámbula, Rubén
Publicado: (1966)

EMSY links breast cancer gene 2 to the 'Royal Family'
por: Yao, Jun, et al.
Publicado: (2004)

Dissecting the mammary gland one cell at a time
por: Cristea, Simona, et al.
Publicado: (2018)

Bioenergetic Impairment in Congenital Muscular Dystrophy Type 1A and Leigh Syndrome Muscle Cells
por: Fontes-Oliveira, Cibely C., et al.
Publicado: (2017)

Bone Marrow Mesenchymal Stem Cell‐Derived Dermcidin‐Containing Migrasomes enhance LC3‐Associated Phagocytosis of Pulmonary Macrophages and Protect against Post‐Stroke Pneumonia
por: Li, Tiemei, et al.
Publicado: (2023)

Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling
por: Wandinger, Sebastian K., et al.
Publicado: (2016)

ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC
por: Alvarado, Diego, et al.
Publicado: (2017)

Unraveling the complexity of basal-like breast cancer
por: Marotta, Lauren L. C., et al.
Publicado: (2011)

Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB3(80kDa) in Prostate Cancer Progression
por: El Maassarani, Mahmoud, et al.
Publicado: (2016)

The Effect of Acetyl Salicylic Acid Induced Nitric Oxide Synthesis in the Normalization of Hypertension through the Stimulation of Renal Cortexin Synthesis and by the Inhibition of Dermcidin Isoform 2, A Hypertensive Protein Production
por: Ghosh, Rajeshwary, et al.
Publicado: (2014)

Effects of ErbB2 Overexpression on the Proteome and ErbB Ligand-specific Phosphosignaling in Mammary Luminal Epithelial Cells
por: Worthington, Jenny, et al.
Publicado: (2017)

Cachexia: a problem of energetic inefficiency
por: Argilés, Josep M., et al.
Publicado: (2014)

Effects of metformin on congenital muscular dystrophy type 1A disease progression in mice: a gender impact study
por: Fontes-Oliveira, Cibely C., et al.
Publicado: (2018)

Strategy to reduce antibiotic prescription in cases of airway aspiration
por: Bagnulo, H, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_h91n73m9ik4mutq5v9me92iec6