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The H(2)S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis

BACKGROUND: In experimental periodontitis, non-steroidal antiinflammatory drugs (NSAIDs) effectively inhibit the resultant alveolar bone loss. However, their deleterious gastric effects, observed in both animals and humans, dramatically limit their long-term use. It has been proven that the addition...

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Detalles Bibliográficos
Autores principales: Herrera, Bruno Schneider, Coimbra, Leila Santana, da Silva, Agatha Ribeiro, Teixeira, Simone Aparecida, Costa, Soraia Katia Pereira, Wallace, John Lawrence, Spolidorio, Luis Carlos, Muscara, Marcelo Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353461/
https://www.ncbi.nlm.nih.gov/pubmed/25755876
http://dx.doi.org/10.1186/s13618-015-0025-3