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The H(2)S-releasing naproxen derivative, ATB-346, inhibits alveolar bone loss and inflammation in rats with ligature-induced periodontitis
BACKGROUND: In experimental periodontitis, non-steroidal antiinflammatory drugs (NSAIDs) effectively inhibit the resultant alveolar bone loss. However, their deleterious gastric effects, observed in both animals and humans, dramatically limit their long-term use. It has been proven that the addition...
Autores principales: | Herrera, Bruno Schneider, Coimbra, Leila Santana, da Silva, Agatha Ribeiro, Teixeira, Simone Aparecida, Costa, Soraia Katia Pereira, Wallace, John Lawrence, Spolidorio, Luis Carlos, Muscara, Marcelo Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353461/ https://www.ncbi.nlm.nih.gov/pubmed/25755876 http://dx.doi.org/10.1186/s13618-015-0025-3 |
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