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Induction of CD44 Variant 9-Expressing Cancer Stem Cells Might Attenuate the Efficacy of Chemoradioselection and Worsens the Prognosis of Patients with Advanced Head and Neck Cancer

BACKGROUND: At our institute, a chemoradioselection strategy has been used to select patients for organ preservation on the basis of response to an initial 30–40 Gy concurrent chemoradiotherapy (CCRT). Patients with a favorable response (i.e., chemoradioselected; CRS) have demonstrated better outcom...

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Detalles Bibliográficos
Autores principales: Aso, Takeichiro, Matsuo, Mioko, Kiyohara, Hideyuki, Taguchi, Kenichi, Rikimaru, Fumihide, Shimokawa, Mototsugu, Segawa, Yuichi, Higaki, Yuichiro, Umeno, Hirohito, Nakashima, Tadashi, Masuda, Muneyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353624/
https://www.ncbi.nlm.nih.gov/pubmed/25751671
http://dx.doi.org/10.1371/journal.pone.0116596