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RNA regulons in Hox 5′UTRs confer ribosome specificity to gene regulation

Emerging evidence suggests a regulatory function of the ribosome in directing how the genome is translated in time and space. However, how this regulation is encoded in mRNA sequence remains largely unknown. Here we uncover unique RNA regulons embedded in Homeobox (Hox) 5′UTRs that confer ribosome-m...

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Detalles Bibliográficos
Autores principales: Xue, Shifeng, Tian, Siqi, Fujii, Kotaro, Kladwang, Wipapat, Das, Rhiju, Barna, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353651/
https://www.ncbi.nlm.nih.gov/pubmed/25409156
http://dx.doi.org/10.1038/nature14010